MODERN METHODS OF DRUG QUALITY CONTROL IN PHARMACEUTICS
Abstract
This article provides a systematic analysis of modern analytical and instrumental methods used in pharmaceutical quality control. The quality of a medicinal product is directly linked to its safety and efficacy, and ensuring the unity of these three factors constitutes the primary objective of international pharmaceutical practice. Over the past decade, high-performance liquid chromatography (HPLC), mass spectrometry, near-infrared spectroscopy (NIR), nuclear magnetic resonance (NMR), and real-time monitoring technologies have been widely implemented in manufacturing processes. The article also discusses the regulatory foundations of quality control within the frameworks of ICH, USP, EP, and the State Pharmacopoeia, the concept of Process Analytical Technology (PAT), and the impact of digital transformation on quality control. The findings demonstrate that the optimal combination of analytical methods and continuous process monitoring represents the most effective approach to ensuring consistent drug quality.
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