SYNTHESIS OF HETEROCYCLIC PHYTOHORMONES WITH POLYPHENOLS AND STUDY OF THEIR BIOLOGICAL ACTIVITY
Abstract
This article presents the results of research focused on the synthesis of heterocyclic phytohormone–polyphenol compounds, the elucidation of their structure–activity relationships, and the study of their biological properties. Phytophormones are natural biologically active substances that regulate the growth and development of plants. By combining them with antioxidant compounds belonging to the polyphenol class, it is possible to obtain novel complexes with enhanced biological activity. The synthesized heterocyclic–polyphenol derivatives were evaluated for their antioxidant, antimicrobial, antifungal, and plant growth–stimulating effects. The findings indicate that these compounds hold great potential for application in agriculture, pharmaceuticals, and biotechnology. The paper also discusses synthesis routes, structural characterization methods (IR, UV, and NMR spectroscopy), and approaches to determining biological activity in detail.
References
1. Abdurahmonov, Q. (2020). Fundamentals of Organic Chemistry and Their Biological Significance. Tashkent: Fan Publishing.
2. Ahmadjonova, M. (2021). The Role of Phytohormones in Plant Physiology. Tashkent: National University of Uzbekistan Publishing.
3. Andersen, Ø. M., & Markham, K. R. (2006). Flavonoids: Chemistry, Biochemistry and Applications. CRC Press.
4. Belov, N. A. (2020). Phytohormones and Plant Growth Regulators. Moscow: Nauka.
5. Davies, P. J. (2010). Plant Hormones: Biosynthesis, Signal Transduction, Action!. Springer.
6. Ergashev, D. (2022). Polyphenols and Their Antioxidant Properties. Samarkand: SamDU Publishing.
7. Gromov, V. I., & Mishin, A. A. (2021). Biologically Active Compounds of Natural Origin. Saint Petersburg: Khimiya.
8. Halliwell, B., & Gutteridge, J. M. C. (2015). Free Radicals in Biology and Medicine. Oxford University Press.
9. Ismoilov, B. (2020). Biochemistry and the Chemistry of Bioactive Compounds. Tashkent: TDPU Publishing.
10. Ivanova, E. N. (2019). Phenolic Compounds and Their Antioxidant Properties. Moscow: RKhTU.
11. Jo‘rayev, A. (2023). Natural Complexes Stimulating Plant Growth. Tashkent: Innovatsiya.
12. Karimova, N. (2021). Phytochemistry and Fundamentals of Ecological Biotechnology. Tashkent: Society of Philosophers of Uzbekistan.
13. Khusnutdinova, E., & Crabtree, R. H. (2017). Complexes of Natural Products with Metal Ions and Their Biological Activity. Elsevier.
14. Kuznetsov, V. V. (2022). Plant Physiology with Elements of Biochemistry. Moscow: Akademkniga.
15. Matkarimov, S. (2022). Organic Synthesis and the Structure of Bioactive Compounds. Tashkent: Higher Education.
16. Orlova, T. A. (2023). Phytohormone–Polyphenol Complexes: Chemistry and Biological Activity. Novosibirsk: SO RAN.
17. Rasulov, H. (2019). Plant Biotechnology and Growth Stimulators. Tashkent: UZMU Publishing.
18. Taiz, L., Zeiger, E., Møller, I. M., & Murphy, A. (2015). Plant Physiology and Development. Sinauer Associates.
19. Tursunov, U. (2023). Chemistry of Biostimulants and Their Practical Application. Fergana: FDU Publishing.
20. Yo‘ldoshev, I. (2021). Natural Polyphenols and Their Biological Role. Tashkent: Science and Technology Publishing.
